Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 482-220-0 | CAS number: 848301-69-9
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
- NOEC (28 d): ≥1000 mg/kg sediment dw test mat. (nominal) based on: development rate
- EC50 (28 d): >1000 mg/kg sediment dw test mat. (nominal) based on: development rate
- NOEC (28 d): 560 mg/kg sediment dw test mat. (meas. (arithm. mean)) based on: mortality and emergence ratio
- EC50 (28 d): >1000 mg/kg sediment dw test mat. (nominal) based on: mortality and emergence ratio
Key value for chemical safety assessment
Additional information
The toxicity of the substance has been determined in a test with the sediment organism Chironomus tentans. The test was conducted in accordance with OECD Test Guideline 218.
Chironomus tentans were exposed to formulated spiked sediment nominal loading rates of 100, 180, 320, 560 and 1000 mg/kg of test material over a period of 28 days. The study was carried out according to GLP and analytical monitoring took place. Analytical work on the ‘wet’ sediment was problematic, therefore analysis on the ‘dry’ sediment was also carried out.
The test results, expressed as the EC50and NOEC values, showed that the sample was not toxic to sediment organisms at 1000 mg/kg over the time period tested.
Analysis of the ‘dry’ sediment on the day of preparation (Day -7) showed measured concentrations to range from 90% to 111% of nominal. Analysis of the overlying and interstitial pore water on Days 0 and 28 showed measured concentrations to be <LOQ.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
