Registration Dossier
Registration Dossier
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EC number: 242-053-4 | CAS number: 18169-57-8
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
There are no test data for the substance. However a 96-hour LC50 value of >100 mg/L has been determined for the effects of a related substance, Trimethoxy(2-methylpropyl)silane (CAS 18395-30-7), on mortality of Brachydanio rerio. It is likely that the test organisms were exposed to the hydrolysis products of the substance.
Key value for chemical safety assessment
Additional information
No test data for short-term toxicity to fish are available for Trichloroisobutylsilane. However a study of short-term toxicity to fish is available for the related substance Trimethoxy(2-methylpropyl)silane. Trichloroisobutylsilane (CAS 18169-57-8) and Trimethoxy(2-methylpropyl)silane (CAS 18395-30-7) both hydrolyse to isobutylsilanetriol. The hydrolysis half-lives of Trichloroisobutylsilane and Trimethoxy(2-methylpropyl)silane indicate that, under conditions relevant to ecotoxicity assessment, they will hydrolyse to isobutylsilanetriol over the course of the tests. The other hydrolysis products are hydrogen chloride and ethanol, respectively; the properties of these substances are well characterised. Ethanol is non-toxic to the environment and it is considered unlikely its presence significantly affected the results of the test performed with Trimethoxy(2-methylpropyl)silane. Effects of hydrogen chloride on aquatic organisms are limited to those that result from changes to pH in unbuffered media.
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