Registration Dossier
Registration Dossier
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EC number: 200-795-6 | CAS number: 73-22-3
Endpoint summary
Administrative data
Description of key information
Additional information
The ready biodegradation of L-tryptophan was investigated in a study conducted according to OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test) over a period of 28 days and using non-adapted activated sludge as inoculum. The test item proved to be readily biodegradable and fulfilling the 10-d-window criterion (77% biodegradation after 28 d). The functional control reached the pass level > 60% after 14 d. In the toxicity control containing both test and reference item 75% biodegradation based on ThCO2 occurred within 14 d thus indicating that the test item was not inhibitory at the concentration tested. According to REACH Regulation (Annex IX, 9.2.1.2 and 9.2.1.4, column 2), the study on biodegradation in water and sediment (simulation tests) does not need to be done if the test substance is readily biodegradable. L-Tryptophan proved to be readily biodegradable. According to REACH Regulation (Annex IX, 9.2.1.3, column 2), the study on biodegradation in soil does not need to be done if the the test substance is readily biodegradable. L-Tryptophan proved to be readily biodegradable.
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