Registration Dossier
Registration Dossier
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EC number: 270-307-4 | CAS number: 68424-50-0
Endpoint summary
Administrative data
Description of key information
The substance is of no concern for repeated dose / subacute toxicity
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 1 000 mg/kg bw/day
- Study duration:
- subacute
- Species:
- rat
Repeated dose toxicity: inhalation - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
The oral route was considered representative for these fat liquors. Dermal and inhalation studies were not conducted.No data are available for the substance. Read across from similar substances (sulfited fat liquors EC 307-037-4 fish oil and EC 281-975-1 rape oil) indicate that no effects were seen at the highest concentration tested, therefore the 'No Observed Adverse Effect Level' (NOAEL) for systemic toxicity and reproductive toxicity was considered to be 1000 mg/kg/day. There were no treatment related effects or abnormalities observed.
Justification for selection of repeated dose toxicity via oral route - systemic effects endpoint:
Fish oil derivative has been selected as representative similar substance since the molecular chain distribution is not only focused on C16-C18 but also components C20 and higher has been taken in to account.
Justification for classification or non-classification
Based on existing studies the substance is not classified for repeated dose toxicity according to CLP criteria set out in Regulation 1272/2008
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