Registration Dossier
Registration Dossier
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EC number: 202-770-5 | CAS number: 99-59-2
Endpoint summary
Administrative data
Description of key information
Additional information
Biodegradation in water:-
Based on the information collected from various sources for the biodegradation in water for 5-nitro-o-anisidine it was estimated that 5-nitro-o-anisidine degrades 87% in 28 days thus it can be concluded that 5-nitro-o-anisidine is readily biodegradable in water medium.
The summary of the results are presented below
Sr. No |
Endpoint name |
Value |
Units |
Duration |
1 |
% Degradation |
87 |
% |
28 d |
2 |
% Degradation |
50 |
% |
38 d |
Based on the above information it can be concluded that the substance is readily biodegradable. Also the half life of 5-nitro-o-anisidine is less than 60 days the threshold criteria for persistence it can be concluded that 5-nitro-o-anisidine is not persistent in water according to criteria of CLP regulation.
Biodegradation in water and sediment:
The half life period of 5 -nitro-o-anisidine in water is observed to be 912 h (38 days) while in sediment it is 8160 h (340 days). Based on these half life values of 5 -nitro-o-anisidine, it is concluded that the chemical is readily biodegradable in water where as it is non biodegradable in sediment. However, since there is no diffusion of the substance in the sediment as evident from the reported data (0% in sediment) and hence persistence in the sediment compartment is not likely to be critical.
Biodegradation in soil:
Based on QSAR prediction half life period of 5-nitro-o-anisidine in Soil was estimated to be 139 days.
Also from the other weight of evidnece study it is found that the substance is 50% degradable in 75 days which exceeds the EPA criteria of 60 days
Based on these half life values it is concluded that 5-nitro-o-anisidine is not readily biodegradable (persistent) in Soil.
No. of studies reviewed for biodegradation in water endpoints from reliable sources having Klimish rating 2
The summary of the results are presented below.
Sr. No |
Endpoint name |
Value |
Units |
Half life |
||
| 1 | % degradation | 50 | % | 139d | ||
| 2 | %degradation | 50 | % | 75d | ||
Based on the above information it can be concluded that the substance is not readily biodegaradable and hence persistent in Soil according to CLPregulation.
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