Registration Dossier
Registration Dossier
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EC number: 231-598-3 | CAS number: 7647-14-5
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
21 day NOEC (reproduction, Daphnia pulex)= 314 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 314 mg/L
Additional information
Three relevant studies have been identified for chronic toxicity to invertebrates. All three have been performed with water fleas: Daphnia pulex, Daphnia magna, and Cerodaphnia dubia. However, in the study by Birge et al. (1985) additional invertebrate species were tested in acute toxicity testing together with Daphnia pulex (Lirceus fontinalis, an isopod and Physa gyrina, a pond snail – data not summarised in this dataset). In this testing Daphnia pulex was found to be the most sensitive species. Again, when comparing the results from the three chronic testing with water flea
presented in this data set , Daphnia pulex remains the most sensitive species with a NOEC for reproduction (and other endpoints) of 314 mg/L (LOEC: 441 mg/L). The result is in good agreement with the geometric mean of the NOEC for reproduction from 12 independent 7d exposure with Cerodaphnia dubia (NOEC=353 mg/L).Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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