Registration Dossier
Registration Dossier
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EC number: 219-210-0 | CAS number: 2387-03-3
Endpoint summary
Administrative data
Description of key information
Additional information
Hydriolysis:
The Hydrolysis rate constant of 1-Naphthalenecarboxaldehyde, 2-hydroxy-, (2-hydroxy-1-naphthalenyl)methylene hydrazone is estimated to be 0.00000000020416 cm3/molecule-sec at half-life of 0.629hrs. The estimated half-life of the substance indicates that the substance 1-Naphthalenecarboxaldehyde, 2-hydroxy-, (2-hydroxy-1-naphthalenyl)methylene hydrazone is rapidly hydrolysable.
Biodegradation in water: screening tests
A number of studies for the test compoundC.I. Pigment Yellow 101(CAS no 2387-03-3) were reviewed for the biodegradation end point which are summarized as below:
During determination of the Biodegradability in the C02-Evolution Test[BASFStudy Report, Sustainability Support Services (Europe) AB(Report no.01/0031/22/1), 2002]according to OECD Guideline 301 B, the Biodegradation degree (C02 to ThCO2) after 28 days of the test substance LUMOGEN GB 0790 ST. BER. 100% was found to be <10 % which indicate that the test substance LUMOGEN GB 0790 ST. BER. 100% is poorly biodegradable (not readily biodegradable according to OECD criteria).
Estimation Programs Interface Suite (EPI suite) was run to predict the biodegradation potential of the test compoundC.I. Pigment Yellow 101(CAS no 2387-03-3). The screening test inherent to the biodegradability of the substance was calculated using the software BIOWIN v4.10. The results indicate thatC.I. Pigment Yellow 101is not expected to be readily biodegradable.
Biodegradation in water ability was predicted for the test compoundC.I. Pigment Yellow 101(CAS no 2387-03-3) using the SSS QSAR prediction model. The ready biodegradability of the test substanceC.I. Pigment Yellow 101after 28 days was estimated as 23.059% by using DOC removal parameter. This result indicates thatC.I. Pigment Yellow 101is not expected to be readily biodegradable in water.
Biodegradation in water and sediment: simulation tests
Half life period of 1-Naphthalenecarboxaldehyde, 2-hydroxy-, (2-hydroxy-1-naphthalenyl)methylene hydrazone in water is observed to be 37.5 days (900 hrs.) while in sediment it is 337.5 days (8100 hrs). Based on these half life values of 1-Naphthalenecarboxaldehyde, 2-hydroxy-, (2-hydroxy-1-naphthalenyl)methylene hydrazone, it is concluded that the chemical is not persistent in water and persistent in sediment.Half life period of 1-Naphthalenecarboxaldehyde, 2-hydroxy-, (2-hydroxy-1-naphthalenyl)methylene hydrazone in water is observed to be 37.5 days (900 hrs.) while in sediment it is 337.5 days (8100 hrs). Based on these half life values of 1-Naphthalenecarboxaldehyde, 2-hydroxy-, (2-hydroxy-1-naphthalenyl)methylene hydrazone, it is concluded that the chemical is not persistent in water and persistent in sediment.
Biodegradation in soil
EPI Suite has estimated that 1-Naphthalenecarboxaldehyde, 2-hydroxy-,(2-hydroxy-1-naphthalenyl)methylene hydrazone is expected to be found not predominantly in soil and it’s not persistence estimate is based on its transformation in this medium. Its half-life in soil, 75 days (1800 hrs), does not exceeds the threshold of 120 days as per Annex XIII of REACH. Therefore, 1-Naphthalenecarboxaldehyde, 2-hydroxy-,(2-hydroxy-1-naphthalenyl)methylene hydrazone is estimated to be not persistent in the soil environment.
Bioaccumulation: aquatic/sediment
A number of studies for the test compound C.I. Pigment Yellow 101 (CAS no 2387-03-3) and its predicted data were reviewed for the bioaccumulation end point which are summarized as below:
The estimated (EPI suite, 2016) bioconcentration factor (BCF) for 1-Naphthalenecarboxaldehyde, 2-hydroxy-, (2-hydroxy-1-naphthalenyl)methylene hydrazone is 4989 L/kg, that exceed the bioconcentration threshold of 2000. Thus it is concluded that 1-Naphthalenecarboxaldehyde, 2-hydroxy-, (2-hydroxy-1-naphthalenyl)methylene hydrazone is expected to bioaccumulate in the food chain because it exceed the BCF criteria.
The estimated (SciFinder, American Chemical Society (ACS); 2016)BCF values for the test chemical at 25°C are as follows: 404 at pH 1, 477 at pH 2, 1190 at pH 3, 7130 at pH 4, 26600 at pH 5, 37100 at pH 6, 36400 at pH 7, 21900 at pH 8, 2430 at pH 9, 48.8 at pH 10, respectively.
Adsorption / desorption
A number of studies for the test compoundC.I. Pigment Yellow 101(CAS no 2387-03-3) and its predicted data were reviewed for the adsorption/desorption end point which are summarized as below:
The soil adsorption coefficient (Koc) value (EPI suite, 2016) of 1-Naphthalenecarboxaldehyde, 2-hydroxy-, (2-hydroxy-1-naphthalenyl)methylene hydrazone is estimated to be 11130000 L/kg, indicating that it is has a high sorption to soil and sediment and therefore have negligible migration potential to groundwater.
From PBT profiler the soil adsorption coefficient (Koc) value of 1-Naphthalenecarboxaldehyde, 2-hydroxy-, (2-hydroxy-1-naphthalenyl)methylene hydrazone is estimated to be 11000000 L/kg i.e log Koc=7.041, indicating that it is has a Very strong sorption to soil and sediment and therefore have negligible migration potential to groundwater.
In the adsorption/desorption study (Asmaa Mawad; et. al, 2015), a biofilm ofAspergillus terreussupported on activated carbon was used as a biological tool for removal of these dyes from water body. The adsorption kinetics and contact time were determined along 240 minutes (30 minute interval). The initial concentration of dyes was 100 mg/L for each one. The optimum pH value for adsorption process was 3.0. The results depicted that the contact time for biosorption of both dyes was 180 min while adsorption kinetics was quietly fitted with Pseudo second-order kinetics equation models. The maximum adsorption capacity was 78.2 mg/g for Pigment Yellow 101.
The estimated (SciFinder, American Chemical Society (ACS); 2016)koc values for the test chemical measured at 25°C for different values of pH are as follows: 694 at pH =1, 819 at pH=2, 2050 at pH=3, 12200 at pH=4, 45800 at pH=5, 63800 at pH=6, 62500 at pH=7, 37700 at pH=8, 4180 at pH=9, 83.9 at pH=10, respectively.
Overall all studies from predicted models and experimental study indicate that the test substance have tendency to high sorption to soil and sediment and therefore have negligible migration potential to groundwater.
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