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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The reaction mass of hexadecyl isocyanate and octadecyl isocyanate, as defined in section 1, consists of 35 % of hexadecyl isocyanate and 65 % of octadecyl isocyanate. Therefore, octadecyl isocyanate was considered to estimate the toxicity of the substance to fish.
A 48 hour EC50 of > 1000 mg/L was determined. No adverse symtoms were observed.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 000 mg/L

Additional information

"should read > 1000 mg/l"

There is no reliable data available for the test substance itself. But as results are present for one main constituents of the reaction mass (65%), this data is taken into account for further assessment as read-across approach. It is assumed that due to the similarity of the chemical structures of both main constituents the ecotoxicological hazards of the reaction mass can be described with data of one or both main components as a realistic approach.