Registration Dossier
Registration Dossier
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EC number: 276-038-9 | CAS number: 71808-53-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
There is no sensitisation data available forC12-18-alkylbis(hydroxyethyl)methyl, chloride (CAS no 71808-53-2).An available in vivo skin corrosion study indicates thatthe substanceis highly corrosive. There is no consumer exposures identified, only industrial/professional use, consequently, due to limited exposures, animal testing is not required.
Migrated from Short description of key information:
No animal test data available. In accordance with column 2 of REACH Annex VII, an in vivo skin sensitisation study does not need to be conducted as the substance is classified as corrosive to the skin.
Justification for selection of skin sensitisation endpoint:
In accordance with column 2 of REACH Annex VII, an in vivo skin sensitisation study does not need to be conducted as the substance is classified as corrosive to the skin.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
C12-18-alkylbis(hydroxyethyl)methyl, chloride (CAS no 71808-53-2) is a handled as a liquid and has a low vapour pressure of 0.00073 Pa at 20°C. Its use is limited to industrial and professional users and does not include formation of aerosols, particles or droplets of inhalable size.Exposure to humans via the inhalation route is therefore considered to be unlikely.
Justification for classification or non-classification
Based on limited exposures by dermal route (substance is severely corrosive) or by inhalation (very low vapour pressure and no generation of aerosols, dust or droplets of inhalable size), sensitisation is expected to be unlikely. However, as a firm conclusion from a study with this compound is lacking, no definite conclusion might be drawn for classification purposes.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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