Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

The acute oral LD50 of N,N'-1,6-hexanediylbis(N-(2,2,6,6-tetramethyl-piperidin-4-yl)formamide was > 2200 mg/kg bw in rats; no mortatily, no clinical signs and no gross pathological findings were observed.
No mortality was observed in an acute aerosol inhalation toxicity study up to the highest concentration tested, which was 5000 mg/m³. Accelerated breathing during exposure. Reddish incrustated noses (day 1 of observation period). No gross pathological findings were observed. The LC50 was > 5000 mg/m³.
A test on acute dermal toxicity was not performed.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 200 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
5 000 mg/m³

Additional information

Justification for classification or non-classification

No classification required according to EU-Directive 67/548/EEC, Annex I.

No classification required according to Regulation (EC) No 1272/2008, Annex VI.