Registration Dossier
Registration Dossier
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EC number: 700-751-0 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
CAS 65997-04-8 rosin, fumarated, and the two other members of the category rosin adducts that have been tested using the mouse LLNA assay have been found to be skin sensitisers.Further, one member of the category was also tested by GPMT and Buehler and found positive when these tests were performed.
The data have been published in the scientific literature (Illing, H P A, Malmfors, T and Rodenburg, L 'Skin sensitisation and possible groupings for 'read across' for rosin based substances'. Regulatory Toxicology and Pharmacology 54, 234 -241 (2009)).
Migrated from Short description of key information:
CAS 65997-04-8 rosin, fumarated, and the other rosin adducts that have been tested using the mouse LLNA assay have been found to be skin sensitisers. Further, one similar substance was also tested by GPMT and Buehler and found positive when these tests were performed. As the Ca/Mg salt of rosin fumarated is considerd similar to those substances, it is also classified as sensitising.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
