Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 293-036-3 | CAS number: 91050-89-4
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (3 h) > 10000 mg/L (OECD 209)
Key value for chemical safety assessment
Additional information
Studies investigating the toxicity of Fatty acids, C8-10, triesters with trimethylolpropane (CAS 91050-89-4) to microorganisms are not available. The evaluation therefore refers to the category member Decanoic acid, ester with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol octanoate (CAS 11138-60-6) as part of a read across approach. The read across is based on the comparable fatty acid chain lengthof both substances. This is in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach. Further justification is given within the endpoint summary 6.1 and within the analogue justification section 13. The toxicity of the read-across substance Decanoic acid, ester with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol octanoate (CAS-No. 11138-60-6) was tested in a GLP guideline study following OECD 209 (Kuttler, 1998). The respiration rate of domestic activated sludge was observed at a substance concentration of 10000 mg/L. The test was terminated after 3 hours of incubation. An inhibition of the respiration rate was not observed. Thus an EC10 > 10000 mg/L (nominal) was reported.
The results obtained for the structurally related read-across substance of Decanoic acid, ester with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol octanoate (CAS-No. 11138-60-6) indicate that Fatty acids, C8-10, triesters with trimethylolpropane (CAS 91050-89-4) will not affect the respiration rate of microorganisms. As it can be seen in the data matrix of the category justification in section 13 and the overall endpoint summary IUCLID 6.1, all reliable data in the category support the hazard assessment of each category member by showing a consistent pattern of results, i.e. no microbial inhibition and no toxic effects were observed to aquatic organisms up to the limit of water solubility.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
