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Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
18 Jan-28 Jun 1991
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
Also according to GLP.
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
1984
GLP compliance:
yes
Type of method:
column elution method
Water solubility:
< 0 g/L
Temp.:
20 °C
pH:
5.7

Results:

Test sample

Measured peak height (mm)

Water solubility (μg/mL)

Water solubility

(g/L)

pH

1

5

<0.05230

<5.2 x 10-5

5.70

2

5

<0.05230

<5.2 x 10-5

5.80

3

4

<0.05230

<5.2 x 10-5

6.13

4

3

<0.05135

<5.1 x 10-5

5.92

5

4

<0.05230

<5.2 x 10-5

5.88

pH of blank solution: 6.00, 5.92 and 6.30

Conclusions:
Interpretation of results: insoluble (< 0.1 mg/L)
The water solubility of the test item at 20°C and pH = 5.7 was < 5.2 x 10-5 g/L
Executive summary:

The water solubility of the test item was determined according to the EC A.6 method in compliance with GLP. The solubility was below the detection limit for all measurements. It was therefore concluded that the water solubility of the test item was < 5.2 x 10 -5 g/L.


Description of key information

< 5.2 E-05 g/L at 20 °C, pH = 5.7

Key value for chemical safety assessment

Water solubility:
0 g/L
at the temperature of:
20 °C

Additional information

The water solubility of the substance was determined according to EEC Method A.6 (1984). The column elution method was applied. The substance is insoluble in water.