Registration Dossier
Registration Dossier
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EC number: 940-726-3 | CAS number: 1174522-09-8
Endpoint summary
Administrative data
Description of key information
There is data available for this substance. Attitionally, key, weight-of-evidence and supporting data is available for structural analogues. The data is read across to this substance based on analogue read across and a discussion and report on the read across strategy is provided as an attachment in IUCLID Section 13.
The substances are poorly soluble and made of constituents with various water solubility. As a consequence, the exposures were performed with Water Accommodated Fractions (WAFs). Therefore, the results are based on nominal loadings.
The toxicity level was never reached in any fish, while some of the experimental studies for aquatic invertebrate, algal or microorganism acute studys showed a toxicity effect. Therefore, this substance is considered to display no acute aquatic toxicity for fish based on an analogue read across approach.
Additional information
Key and weight-of-evidence information is summarised below:
Short-term toxicity to fish
Hyd C8-C10, cyclics, <2% arom 96-h LL50 (mortality) for Oncorhynchus mykiss of 3.6 mg/L
Hyd C10-C12, isoalkanes, <2% arom LL50 value for Oncorhynchus mykiss >1000 mg/L. No mortality was observed in either the control or treatment systems.
Hyd C10-C13, nic, <2% arom 96-h LL50 (mortality) for Oncorhynchus mykiss >1000 mg/L. No mortality was observed in either the control or treatment systems.
Hyd C13-C16, n-alkanes, <2% arom 96-h LL50 (mortality) for fathead minnow (Pimephales promelas) >76800 mg/L
Long-term toxicity to fish
A 32 day NOELR value of ≥100 mg/l (loading rate WAF) (highest concentration tested) has been determined for the effects of the test substance on hatching, survival and growth of Pimephales promelas.
Short-term toxicity to aquatic invertebrates
The test substance is poorly soluble and made of constituents with various water solubility. As a consequence, the exposures were performed with Water Accomodated Fractions (WAFs). Therefore, the results are based on nominal loadings and the LC50 value given below is actually a LL50 (lethal loading) value. The 48h-LL50 is > 100 mg/l.
Long-term toxicity to aquatic invertebrates
21-day NOELR = ≥100 mg/l loading rate WAF for the effects of Shell GTL Solvent GS170 (Hydrocarbons C9-C12, n-alkanes, isoalkanes, <2% aromatics) on mobility and reproduction of Daphnia magna. EL10 and EL50 values of >100 mg/l loading rate WAF were also determined.
Toxicity to algae and cyanobacteria
GC analysis of each individual constituent in the 100 mg/L loading rate WAF test preparations at 0 and 72 hours showed measured concentrations of less than the limit of quantification (LOQ). Given that the toxicity cannot be attributed to a single component or a mixture of components but to the test item as a whole, the results were based on nominal loading rates only. Exposure of Pseudokirchneriella subcapitata to the test item gave EL50 values of greater than 100 mg/L loading rate WAF. The No Observed Effect Loading Rate was 100 mg/L loading rate WAF. It was considered unnecessary and unrealistic to test at loading rates in excess of 100 mg/L loading rate WAF.
Total Organic Carbon (TOC) analysis of the 100 mg/L loading rate WAF test preparations at 0 and 72 hours showed measured carbon concentrations of less than the limit of quantification (LOQ), determined to be 1.0 mg C/L were obtained. Given that the toxicity cannot be attributed to a single component or a mixture of components but to the test item as a whole, the results were based on nominal loading rates only. Exposure of Pseudokirchneriella subcapitatata the test item gave EL50 values of greater than 100 mg/L loading rate WAF. The No Observed Effect Loading Rate was 100 mg/L loading rate WAF. It was considered unnecessary and unrealistic to test at loading rates in excess of 100 mg/L loading rate WAF.
Toxicity to microorganisms
The aquatic toxicity was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
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