Registration Dossier
Registration Dossier
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EC number: 246-386-6 | CAS number: 24650-42-8
Developmental toxicity / teratogenicity
Administrative data
- Endpoint:
- developmental toxicity
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Title:
- No information
- Author:
- Anonymous
- Year:
- 2 013
- Bibliographic source:
- OECD Toolbox v3.1
Materials and methods
Test guideline
- Guideline:
- other: read across
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,2-dimethoxy-1,2-diphenylethan-1-one
- EC Number:
- 246-386-6
- EC Name:
- 2,2-dimethoxy-1,2-diphenylethan-1-one
- Cas Number:
- 24650-42-8
- Molecular formula:
- C16H16O3
- IUPAC Name:
- 2,2-dimethoxy-1,2-diphenylethan-1-one
Constituent 1
Test animals
- Species:
- other: rabbit and rat
Administration / exposure
- Route of administration:
- oral: unspecified
- Duration of treatment / exposure:
- 45d
Results and discussion
Results: maternal animals
Effect levels (maternal animals)
- Key result
- Dose descriptor:
- NOAEL
- Effect level:
- 757 mg/kg bw/day
- Based on:
- test mat.
- Basis for effect level:
- other: developmental toxicity
Results (fetuses)
Effect levels (fetuses)
- Remarks on result:
- other: not specified
Fetal abnormalities
- Abnormalities:
- not specified
Overall developmental toxicity
- Developmental effects observed:
- not specified
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
