Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Remarks:
other: read across
Type of information:
other: OECD Toolbox v3.4 read across study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
see attached OECD Toolbox study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2021
Report date:
2021

Materials and methods

Test guideline
Guideline:
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Oxydi-2,1-ethanediyl bismethacrylate
EC Number:
219-099-9
EC Name:
Oxydi-2,1-ethanediyl bismethacrylate
Cas Number:
2358-84-1
Molecular formula:
C12H18O5
IUPAC Name:
2-{2-[(2-methylprop-2-enoyl)oxy]ethoxy}ethyl 2-methylprop-2-enoate
Test material form:
liquid

Test animals / tissue source

Species:
rabbit

Results and discussion

In vivo

Results
Irritation parameter:
other: irritating/not irritating
Basis:
mean
Time point:
other: not specified
Score:
ca. 0
Max. score:
110
Reversibility:
not specified
Remarks on result:
other: Ecosar class methacrylates, STRICT

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met