Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Studies on the toxicity of Fatty acids, C16-18 (even numbered), esters with glycerol oligomers to terrestrial organisms are not available.
The target substance is characterized by low water solubility (91.9 µg/L at 20 °C; OECD 105, column elution method), low volatilization potential (vapour pressure ≤ 0.00001 Pa at 20 °C, SPARC v4.6), a moderate to high potential for adsorption to organic soil and sediment particles (log Koc = 1.31 – 12.67, KOCWIN v2.00; MCI method) and ready biodegradability. Based on these properties, soil and sediment are expected to be the main compartments for environmental distribution.However, based on the readily biodegradability in combination with low water solubility and high adsorption potential the substance is expected to be eliminated in sewage treatment plant to a high extent. Therefore, release to the aquatic environment and subsequent exposure of the terrestrial compartment is highly unlikely. Indirect exposure of soil via irrigation or atmospheric transport is not expected based on the physico-chemical substance properties.
Furthermore the substance is expected to be rapidly biodegradated in the aquatic or terrestrial compartments if released to the environment. However, the bioavailability in sediment and soil is presumably low based on the high sorption potential and on metabolization pathways. Generally, long-chain aliphatic esters can be expected to be metabolized by microorganisms.Literature provides evidence that long-chain aliphatic esters undergo common metabolic pathways and are excreted or used as energy source for catabolism by both aquatic and terrestrial microorganisms. Therefore, the bioavailability in sediment and soil is presumably low thereby reducing the probability of chronic exposure.
Based on the high log Koc (1.31 – 12.67, KOCWIN v2.00; MCI method) indicating a potential for adsorption to soil particles, tests with soil-dwelling organisms like earthworm which allows potential uptake via surface contact, soil particle ingestion and pore water (Guidance on information requirements and chemical safety assessment, Chapter R.7c, (ECHA, 2017)) are most relevant for the evaluation of soil toxicity of Fatty acids, C16-18 (even numbered), esters with glycerol oligomers. Furthermore, no acute toxicity at > 10 mg/L and chronic or long-term effects in aquatic organisms up to the water solubility limit was observed indicating no selective toxicity for the aquatic compartment. Short-term toxicity data on soil macroorganisms is available for a structurally and chemically related source substance showing no effects on survival or biomass during the exposure period.
Thus, no further study on the effects on terrestrial organisms need to be conducted for Fatty acids, C16-18 (even numbered), esters with glycerol oligomers.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
