Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 265-723-8 | CAS number: 65380-84-9
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Organic solvents: physical properties and methods of purification, 4th edition
- Author:
- Riddick, J.A. et al.
- Year:
- 1 986
- Bibliographic source:
- John Wiley & Sons, Ltd; as cited by EPISuite v4.11
Materials and methods
- Principles of method if other than guideline:
- No information available
- Type of method:
- other: no information available
Test material
- Reference substance name:
- Propan-2-ol
- EC Number:
- 200-661-7
- EC Name:
- Propan-2-ol
- Cas Number:
- 67-63-0
- Molecular formula:
- C3H8O
- IUPAC Name:
- propan-2-ol
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- > 1 000 g/L
- Temp.:
- 25 °C
- Remarks on result:
- other: No information on pH available.
- Remarks:
- Value assigned to substances classified as miscible or infinitely soluble in water.
- Details on results:
- The experimental data was extracted taken from EPI Suite. The developers of KOWWIN assigned a water solubility of 1000 g/L according to the following criteria.
“Approximately 100 compounds in the regression dataset are classified as "miscible" or "infinitely" soluble in water. These compounds were assigned a numeric water solubility of 106 mg/L and regression results constrained estimates to this limit. For example, an unconstrained regression estimates ethylene glycol (which is miscible) to have a water solubility of nearly 107 mg/L; however, any estimate greater than 106 is automatically reduced to 106. To check this numeric assumption of 106 for miscibility, a separate regression was performed excluding these compounds and the results were very close to the regressions that included them.”
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
