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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2009-04-17 to 2009-09-14
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Key result
Water solubility:
0.14 g/L
Conc. based on:
test mat. (dissolved fraction)
Temp.:
24 °C
Remarks on result:
other: Mean water solubility from incubation durations 24, 48, 72 h.

Results for water solubility determinations of the test item are shown in Table 1.

Table 1: Results of water solubility determinations of the test item

Flask

Agitation period (d)

Sample weight (g)

Solv. added (mL)

Final dilution factor

Repetition

Injection

Result (g/L)

Avg. (g/L)

Mean ± SD (g/L)

1

1

0.5059

50

1

1

1

0.139

0.140

0.140 ± 0.001

2

0.140

2

1

0.140

2

0.141

2

2

0.5142

50

1

1

0.141

0.140

2

0.138

2

1

0.140

2

0.141

3

3

0.5163

50

1

1

0.142

0.141

2

0.140

2

1

0.140

2

0.142

Conclusions:
The water solubility of the test item is 0.14 g/L at 24 °C.
Executive summary:

The water solubility of the test item was determined by shake flask method according to OECD 105 and is 0.14 g/L at 24 °C.

Description of key information

The water solubility of the test item was determined by shake flask method according to OECD 105 and is 0.14 g/L at 24 °C.

Key value for chemical safety assessment

Water solubility:
0.14 g/L
at the temperature of:
24 °C

Additional information