Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 283-922-8 | CAS number: 84775-98-4 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Satureja hortensis, Labiatae.
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is classified as corrosive to the skin
- Justification for type of information:
- The study does not need to be conducted because the substance is classified as skin corrosion (Category 1B/1C). The classification of the substance is based on the available data for LD50 or classification of the constituents of the substance according to Guidance on the Application of CLP Criteria – Guidance to regulation (EC) No 1272/2008 ECHA.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Food Flavourings and Compounds of Related Structure I. Acute Oral Toxicity
- Author:
- Jenner P.M., E.C.Hagan, J.M.Taylor, E.L.Cook andO.G. Fitzhugh
- Year:
- 1 964
- Bibliographic source:
- Food Cosmet. Toxicol. Vol. 2, 327-343
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 973
Materials and methods
Test material
- Specific details on test material used for the study:
- Not specified
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Conclusions:
- The calculated value of ATEmix according to the formula in Section 3.1.3.6.1 of Annex I to Regulation (EC) No 1272/2008 is 680,272.
On the basis of the available data on constituents and the criteria for classifying mixtures according to the Regulation (EC) No 1272/2008, the Summer Savory oil is classified as Acute Toxicity (oral) category 4, H302 Harmful if swallowed. - Executive summary:
The study does not need to be conducted because the substance is classified as skin corrosion (Category 1B/1C). The classification of the substance is based on the available data for LD50 or classification of the constituents of the UVCB substance according to Guidance on the Application of CLP Criteria – Guidance to regulation (EC) No 1272/2008 ECHA.
The calculated value of ATEmix according to the formula in Section 3.1.3.6.1 of Annex I to Regulation (EC) No 1272/2008 is 680,272.
The Summer savory oil has 11 known constituents.
The Acute oral toxicity of the oil is calculated on the basis of the available data about LD50 of 2 constituents (Carvacrol, alpha-Terpinene) and the self-classification of 2 other constituents (alpha-Pinene, alpha-Thujene). One constituent (Dipentene/ Limonene) has harmonized classification and it is not classified as acute oral toxicity. Other 6 constituents are with high LD50 values (above 2000 mg/kg bw), they are not classified as acutely toxic via oral route and therefore their LD50 are not taken into account in the calculation.
On the basis of the available data on constituents and the criteria for classifying mixtures according to the Regulation (EC) No 1272/2008, the Summer Savory oil is classified as Acute Toxicity (oral) category 4, H302 Harmful if swallowed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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