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Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
04 June 2019.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
equivalent or similar to guideline
Guideline:
other: Organisation for Economic Co-operation and Development (OECD), OECD Guidelines for Testing of Chemicals, Guideline No. 105, "Water Solubility", adopted July 27, 1995
Qualifier:
equivalent or similar to guideline
Guideline:
other: CIPAC Handbook Volume H, MT 181 “Solubility in Organic Solvents”, 1998
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Lithium 2-aminobenzothiazole-6-sulphonate
EC Number:
265-367-3
EC Name:
Lithium 2-aminobenzothiazole-6-sulphonate
Cas Number:
65072-36-8
Molecular formula:
C7H6N2O3S2.Li
IUPAC Name:
lithium 2-amino-1,3-benzothiazole-6-sulfonate
Test material form:
solid: particulate/powder
Details on test material:
- Bulk Density (g/ml): 0.39
- Particle size distribution (μm): 19.6
- Water solubility: 20%

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
other: n-heptane
Solubility:
< 10 g/L
Temp.:
20 °C
Medium:
other: p-xylene
Solubility:
< 10 g/L
Temp.:
20 °C
Medium:
other: 1,2-dichloroethane
Solubility:
< 10 g/L
Temp.:
20 °C
Medium:
acetone
Solubility:
< 10 g/L
Temp.:
20 °C
Medium:
ethyl acetate
Solubility:
< 10 g/L
Temp.:
20 °C
Medium:
methanol
Solubility:
< 10 g/L
Temp.:
20 °C
Test substance stable:
yes

Applicant's summary and conclusion

Conclusions:
The solubility of lithium 2-aminobenzothiazole-6-sulphonate was evaluated in six organic solvents. In each case, the solubility was determined to be < 10 g/L at room temperature.
Executive summary:

The solubility of lithium 2-aminobenzothiazole-6-sulphonate was evaluated in six organic solvents. In each case, the solubility was determined to be < 10 g/L at room temperature.