Registration Dossier
Registration Dossier
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EC number: 472-110-0 | CAS number: 71868-15-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2007
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.11 (Biodegradation: Activated Sludge Respiration Inhibition Test)
- Version / remarks:
- Annex V, C.11 (Activated sludge - respiration inhibition test)
- GLP compliance:
- yes
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 3 h
- Duration:
- 3 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 100 mg/L
- Duration:
- 3 h
- Dose descriptor:
- NOEC
- Effect conc.:
- > 100 mg/L
- Conclusions:
- Under the study conditions, the 3 h IC50 and NOEC were determined to be >100 mg/L.
- Executive summary:
A study was conducted to determine the toxicity of the test substance to activated sludge microorganisms according to EU Method C.11, comparable to OECD Guideline 209, in compliance with GLP. Microorganisms were exposed to the test substance for 96 h under aerobic conditions. Under the study conditions, the 3 h IC50 and NOEC were both determined to be >100 mg/L (ChemService, 2007).
Reference
Description of key information
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
A study was conducted to determine the toxicity of the test substance to activated sludge microorganisms according to EU Method C.11, comparable to OECD Guideline 209, in compliance with GLP. Microorganisms were exposed to the test substance for 96 h under aerobic conditions. Under the study conditions, the 3 h IC50 and NOEC were both determined to be >100 mg/L (ChemService, 2007).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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