4,4-Dimethyl-2-undecyl-2-oxazoline

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

06-2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Justification for type of information:

The nature of lauryl oxazoline, the manufacture process, the historical knowledge and expertise acquired on the lauryl oxazoline demonstrate a very high solubility of the lauryl oxazoline treated in alcohol such as octanol and a very low solubility in water. To reinforce these criteria, a study has been conducted according to European Pharmacopoeia.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2017

Report date:

2017

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: european pharmacopoeia

Deviations:

no

GLP compliance:

not specified

Type of method:

other: European Pharmacopoeia

Test material

Test material information

Constituent 1

Reference substance name:

4,4-dimethyl-2-undecyl-4,5-dihydro-1,3-oxazole

EC Number:

686-853-5

Cas Number:

46921-17-9

Molecular formula:

C16H31NO

IUPAC Name:

4,4-dimethyl-2-undecyl-4,5-dihydro-1,3-oxazole

impurity 1

Reference substance name:

Unknown impurities

IUPAC Name:

Unknown impurities

impurity 2

Reference substance name:

IUPAC name not applicable

Molecular formula:

C16H33NO2

IUPAC Name:

IUPAC name not applicable

impurity 3

Reference substance name:

IUPAC name not applicable

Molecular formula:

C28H55NO3

IUPAC Name:

IUPAC name not applicable

Test material form:

liquid

Results and discussion

Water solubility

Key result

Water solubility:

< 0.1 mg/L

Conc. based on:

test mat.

Loading of aqueous phase:

10 other: liters

Remarks on result:

other: organic substance : no pH