N,N-dimethylpyridin-4-amine

Guidance on Safe Use

First-aid measures

Skin Contact: Wash exposed area twice with soap and water. The exposed area should be examined by medical personnel. Due to this material's dermal toxicity, it is important to wash the exposed area without delay and GET MEDICAL ATTENTION as soon as possible.

Eye Contact: Rinse eyes immediately with large amounts of water for at least 15 minutes, occasionally lifting the eyelids. GET MEDICAL ATTENTION.

Inhalation: Remove from exposure area to fresh air immediately. If breathing has stopped, give artificial respiration. Keep affected person warm and at rest. GET MEDICAL ATTENTION.

Ingestion: If swallowed, contact physician or poison control center immediately. Give oxygen if respiration is shallow. GET MEDICAL ATTENTION. Do not give anything by mouth to an unconscious person. Due to this material's potential toxicity, it is essential to get medical attention as quickly as possible.

Note to Physician: This material is highly toxic via dermal exposure and is readily absorbed through the skin. Rapid, complete decontamination of the patient is critical (material is slightly water-soluble). No specific antidote known. Treatment should be based on the judgment of the physician in response to the reactions of the patient.

Fire-fighting measures

Appropriate Extinguishing Media: Water fog, Foam, Carbon dioxide, Dry chemical

Hazardous Products of Combustion: Toxic fumes may be released upon thermal decomposition (cyanides, nitrogen oxides, carbon monoxide).

Potential for Dust Explosion: 4-Dimethylaminopyridine (DMAP) prills (pastilles) were tested for dust explosion characteristics and the following results were obtained:

- minimum ignition energy: > 500 mJ

- Minimum ignition temperature of dust cloud: 640-600°C

Special Flammability Hazards: This product is an organic solid. As such, in its finely divided form, this product has the potential to present a dust explosion hazard under certain conditions. Please review the dust explosion data enclosed in this section. Handle this product in a manner that prevents dust generation and accumulation.

Accidental release measures

Evacuation Procedures: Isolate the hazard area and deny entry to unnecessary and unprotected personnel.

Special Instructions: Remove all contaminated clothing to prevent further absorption. Decontaminate affected personnel using the first aid procedures in Section 4. Leather shoes that have been saturated must be discarded. Avoid dust generation during clean-up. Ensure thorough decontamination of the release area and clean-up personnel.

Prevent releases to soils, drains, sewers, and waterways.

Containment Techniques and Clean-up Procedures:

Remove all ignition sources. Ventilate the area of spill or leak. Wear protective equipment during clean-up. Material can then be collected for later disposal. After collection of material, flush area with water. Dispose of the material in accordance with standard practice for disposal of potentially hazardous materials as required by applicable federal, state or local laws. Dust deposits should not be allowed to accumulate on surfaces, as these may form an explosive mixture if they are released into the atmosphere in sufficient concentration.

Avoid dispersal of dust in the air (i.e., clearing dust surfaces with compressed air). Nonsparking tools should be used.

Handling and storage

Precautions for Unique Hazards: This material may present a dust explosion hazard in solid form and is sensitive to ignition by electrostatic discharge. Maintain areas below flammable vapor / explosive dust concentrations.

Practices to Minimize Risk: Wear appropriate protective equipment when performing maintenance on contaminated equipment. Wash hands thoroughly before eating or smoking after handling this material.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

2811

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

2811

Shipping information

Proper shipping name and description:

Toxic solid, organic, n.o.s.

Chemical name:

(4-Dimethylaminopyridine)

Marine pollutant

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

2811

Shipping information

Proper shipping name and description:

Toxic solid, organic, n.o.s.

Chemical name:

(4-Dimethylaminopyridine)

Remarks

SpecialProvisions

Exposure controls / personal protection

Personal Protective Equipment: For handling small quantities outside a laboratory setting: NIOSH-approved full-face chemical cartridge respirator with organic vapor cartridges and HEPA filters; impervious gloves (nitrile or neoprene), poly-coated Tyvek ® coveralls, rubber boots, and face shield as necessary. For handling large quantities: supplied air breathing equipment; impervious gloves (nitrile or neoprene), coveralls, rubber boots, and face shield as necessary.

All operations should be conducted in well-ventilated conditions. Local exhaust ventilation should be provided. It is recommended that all dust control equipment such as local exhaust ventilation and material transport systems involved in handling of this product contain explosion relief vents or an explosion suppression system or an oxygen-deficient environment.

Ensure that dust-handling systems (such as exhaust ducts, dust collectors, vessels, and processing equipment) are designed in a manner to prevent the escape of dust into the work area (i.e., there is no leakage from the equipment).

All appropriate engineering controls should be used to minimize exposure potential. Use exhaust ventilation to keep airborne concentrations below exposure limits. Use only appropriately classified electrical equipment and powered industrial trucks.

Stability and reactivity

Not classified as dangerously reactive. Will not autopolymerize.

Avoid static discharge and uncontrolled exposure to high temperatures.

Avoid contact with strong acids and oxidizing agents.

Toxic fumes may be released upon thermal decomposition (cyanides, nitrogen oxides, carbon monoxide).

Disposal considerations

Dispose of this material in accordance with standard practice for disposal of potentially hazardous materials as required by applicable international, national, regional, state or local laws. Do NOT dump into any sewers, on the ground, or into any body of water. For disposal within the EC, the appropriate code according to the European Waste Catalogue (EWC) should be used. Note that disposal regulations may also apply to empty containers and equipment rinsates.