Registration Dossier
Registration Dossier
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EC number: 285-089-6 | CAS number: 85029-63-6
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- In accordance with Annex XI No 1.2 it is scientifically not necessary to perform an acute dermal toxicity study, because existing data indicate that it can be plausibly assumed that a dermal LD50 of > 2000 mg/kg would result based
- on the findings of an acute oral toxicity study in rats with a LD50 > 2000 mg/kg,
- on the findings of an OECD 422 study with oral application which did not reveal adverse effects up to the limit dose of 1000 mg/kg/d,
- on the plausible assumption that dermal absorption would not exceed oral absorption.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
