Registration Dossier
Registration Dossier
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EC number: 204-582-9 | CAS number: 122-91-8
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- Data from peer reviewed journal
Data source
Reference
- Reference Type:
- publication
- Title:
- Fragrance raw materials monographs: AnisyL Formate
- Author:
- Elsevier Ltd.
- Year:
- 1 976
- Bibliographic source:
- Food and Cosmetics toxicology, volume 14, supplement 1976, page 685
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: refer below principle
- Principles of method if other than guideline:
- In- vitro toxicity study of Anisyl formate on cultures of four bacteria
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Anisyl formate
- EC Number:
- 204-582-9
- EC Name:
- Anisyl formate
- Cas Number:
- 122-91-8
- Molecular formula:
- C9H10O3
- IUPAC Name:
- (4-methoxyphenyl)methyl formate
- Test material form:
- liquid
- Details on test material:
- Details on test material
- Name of test material (as cited in study report): Anisyl Formate
- Molecular formula: C9H10O3
- Molecular weight: 166.175 g/mole
- Substance type: Organic
- Physical state: Liquid
Constituent 1
- Specific details on test material used for the study:
- - Name of test material: (4-methoxyphenyl)methyl formate
- Molecular formula: C9H10O3
- Molecular weight: 166.175 g/mol
- Smiles notation: c1(ccc(OC)cc1)COC=O
- InChl: 1S/C9H10O3/c1-11-9-4-2-8(3-5-9)6-12-7-10/h2-5,7H,6H2,1H3
- Substance type: Organic
- Physical state: Liquid
Sampling and analysis
- Analytical monitoring:
- not specified
- Details on sampling:
- Details on sampling
- Concentrations: 1: 500
- Sampling method: Diluted 1: 500
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- other: Bacteria
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Remarks on exposure duration:
- No details available
Test conditions
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrations
- Key result
- Dose descriptor:
- IC0
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Remarks on result:
- other: No inhibitory effect on growing cultures of four bacteria.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- In- vitro toxicity study, 1: 500 diluted Anisyl formate was tested on cultures of four bacteria. No inhibitory effect on growing cultures of four bacteria was observed. Therefore, IC0 was considered to be 1: 500 diluted for Anisyl formate.
- Executive summary:
From peer reviewed journal Food and Cosmetics toxicology, volume 14, supplement 1976, page 685; In- vitro toxicity study, 1: 500 diluted Anisyl formate was tested on cultures of four bacteria. According to study No inhibitory effect on growing cultures of four bacteria was observed. Therefore, IC0 was considered to be 1: 500 diluted for Anisyl formate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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