4-methoxyphenylacetic acid

Density

Link to relevant study record(s)

Reference

Endpoint:

density, other

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-01-18 – 2017-01-18

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental result performed using standard methods of analysis

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Principles of method if other than guideline:

The density of 4-methoxyphenylacetic acid (CAS No. 104-01-8 ) was determined following OECD guideline 109 and according to the method adapted from ASTM D 854-02.

GLP compliance:

no

Type of method:

pycnometer method

Specific details on test material used for the study:

- Name of the test material: 4-methoxyphenyl)acetic acid
- Molecular formula: C9H10O3
- Molecular weight: 166.175 g/mol
- Substance type: Organic
- Purity: No data

Key result

Type:

density

Density:

1.193 g/cm³

Temp.:

20 °C

Method Details		Observations		Remarks if, any
Guideline	OECD 109	1^stReading	2^nd Reading
Method	Adapted from ASTM 854-02
Principle of method	The density of test item is determined by using pyknometer. It is the ratio of mass of the unit volume of test item at a stated temperature to mass of the same volume of gas free distilled water at a stated temperature.
Test temperature (°C)	-	20^oC	20^oC
Atmospheric pressure (in hPa)	-	977.8	977.5
Weight of empty dry pyknometer (Wp)		30.393	30.358
Weight of pyknometer filled with water (WA)		79.977	79.759
Weight of pyknometer + test Item (WPS)		35.195	34.969
Weight of pyknometer +test Item+ water (WB)		80.789	80.789

 

 

CALCULATIONS:

	Calculated values
	1^stCalculation	2^nd Calculation
Wo=WPS-WP	4.8020	4.6110
(WA-WB)	-0.8120	-0.7369
Specific gravity = WO/[WO+ (WA-WB)]	1.2035	1.1902
Specific Gravity; Gs	1.2035	1.1902
Density (g/cm³)	1.2013	1.1880
Mean Density (g/cm³)	1.1946

Conclusions:

The density of 4-methoxyphenylacetic acid (CAS No. 104-01-8)was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometer. The mean density of test item was determined to be 1.193 g/cm³at 20°C and 977.7hPa.

Executive summary:

The density of 4-methoxyphenylacetic acid (CAS No. 104-01-8)was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometer. The mean density of test item was determined to be 1.193 g/cm³at 20°C and 977.7hPa.

Description of key information

The density of 4-methoxyphenylacetic acid (CAS No. 104-01-8) was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometer. The mean density of chemical 4-methoxyphenylacetic acid was determined to be 1.193 g/cm³ at 20°C and 977.7hPa.

Key value for chemical safety assessment

Relative density at 20C:

1.193

Additional information

The density of 4-methoxyphenylacetic acid (CAS No. 104-01-8) was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometer. The mean density of chemical 4-methoxyphenylacetic acid was determined to be 1.193 g/cm³ at 20°C and 977.7hPa.

Other supporting study from authoritative database also suggests that, the density of chemical 4-methoxyphenyl)acetic acid was reported to be 1.179  g/cm3 at a temperature of 20 °C and  pressure 760 Torr.

As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of density as 1.193 g/cm3 at 20 degree C, thus considered as key study for the chemical safety assessment.