Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 205-793-9 | CAS number: 151-56-4
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Short description of key information on bioaccumulation potential result:
Basic toxicokinetics: supporting studies.
Key value for chemical safety assessment
Additional information
Supporting studies: experimental results from different publications. It is concluded that:
In rat and mouse, i.p.:
- Ethyleneimine caused a marked diuresis and is excreted mainly in urine after injection.
- The major proportion of the ethyleneimine was eliminated within 4 hr of administration. The amount of ethyleneimine excreted within 6 hr and the 3-day urine volume generally increased as the dose of compound was increased.
In rat, oral gavage:
- Ethyleneimine is metabolized to monoethanolamine and both of them are eliminated with the urine, in a rate depending on the harmful level of ethyleneimine (related to LD50) administered.
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