Registration Dossier
Registration Dossier
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EC number: 202-220-4 | CAS number: 93-13-0
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1990
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- [(2-methoxyphenyl)amino]methanesulphonic acid
- EC Number:
- 202-220-4
- EC Name:
- [(2-methoxyphenyl)amino]methanesulphonic acid
- Cas Number:
- 93-13-0
- Molecular formula:
- C8H11NO4S
- IUPAC Name:
- [(2-methoxyphenyl)amino]methanesulfonic acid
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- New Zealand White
Results and discussion
In vivo
Results
- Irritation parameter:
- maximum mean total score (MMTS)
- Basis:
- mean
- Time point:
- other: 72 h
- Score:
- 21.7
- Remarks on result:
- other: Mild irritant without labelling.
Applicant's summary and conclusion
- Interpretation of results:
- slightly irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The test material was also classified as non-irritant to the rabbit eye according to EEC labelling regulations
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