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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1988
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Testing according to OECD209

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1988
Report date:
1989

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
other: EEC-guideline 88/302C
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-methyl-1-p-tolyl-5-pyrazolone
EC Number:
201-708-4
EC Name:
3-methyl-1-p-tolyl-5-pyrazolone
Cas Number:
86-92-0
Molecular formula:
C11H12N2O
IUPAC Name:
3-methyl-1-p-tolyl-5-pyrazolone

Test solutions

Details on test solutions:
Due to the low water solubility no stock solution was used. The test item was weighed out directly into the test vessels.

Test organisms

Test organisms (species):
activated sludge

Study design

Total exposure duration:
3 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
3 h
Dose descriptor:
EC10
Effect conc.:
76.3 mg/L
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
818.1 mg/L
Duration:
3 h
Dose descriptor:
EC100
Effect conc.:
> 1 000 mg/L

Applicant's summary and conclusion

Conclusions:
The EC50 of the tested substance to activated sludge is 818.1 mg/L.