Registration Dossier
Registration Dossier
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EC number: 412-550-2 | CAS number: 85776-14-3 GRAPHTOL ORANGE 3RT; PERMANENT ORANGE 2 RLD; PERMANENT ORANGE 3 RTN
Dissociation constant
Administrative data
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1996
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 996
- Report date:
- 1996
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The study was performed according to the Corning Hezleton Definitive Protocol. The determination of the dissociation constat (pKa) was carried out by potentiometric titration.
- GLP compliance:
- yes
Test material
Constituent 1
Results and discussion
- Dissociating properties:
- not determined
Any other information on results incl. tables
It was not possible to calculatethe pKa value with any degree of accuracy because precipitation of the test substance occured. The color transition observed to occur between pH 10 and pH 12 inpure dioxane, indicated that the ionization values was probably close to pka ~ 11 in pure dioxane. Hence, it is estimated that the aqueous pKa ~ 10.5 +/- 0.5
Applicant's summary and conclusion
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