Registration Dossier
Registration Dossier
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EC number: 233-113-0 | CAS number: 10035-10-6
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- other:
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary source
Data source
Reference
- Reference Type:
- secondary source
- Title:
- HSDB for hydrogen bromide
- Author:
- HSDB
- Year:
- 1 990
- Bibliographic source:
- Connecticut State Department of Health, Hartford, CT, as cited in the Hazardouse Substances Data Base (HSDB), on-line,
Materials and methods
Test material
- Reference substance name:
- Hydrogen bromide
- EC Number:
- 233-113-0
- EC Name:
- Hydrogen bromide
- Cas Number:
- 10035-10-6
- Molecular formula:
- BrH
- IUPAC Name:
- bromide
Constituent 1
Results and discussion
- Results:
- Nose and throat irritation occurred in human subjects exposed to HBr for several minutes at concentrations of 3 ppm (1 of 6 subjects) and 4 ppm (3 of 6 subjects) respectively for several minutes. No effects were observed at 2 ppm, but detectable odor was noted at all exposure levels (2 to 6 ppm). No eye irritation was noted at all concentrations exposed. The odour threshold is given as 6.667 mg/m3 and the irritating concentration as 10.00 mg/m3.
Applicant's summary and conclusion
- Conclusions:
- Nose and throat irritation occurred in human subjects exposed to HBr for several minutes at concentrations of 3 ppm (1 of 6 subjects) and 4 ppm (3 of 6 subjects) respectively for several minutes. No effects were observed at 2 ppm, but detectable odor was noted at all exposure levels (2 to 6 ppm). No eye irritation was noted at all concentrations exposed. The odour threshold is given as 6.667 mg/m3 and the irritating concentration as 10.00 mg/m3.
- Executive summary:
Nose and throat irritation occurred in human subjects exposed to HBr for several minutes at concentrations of 3 ppm (1 of 6 subjects) and 4 ppm (3 of 6 subjects) respectively for several minutes. No effects were observed at 2 ppm, but detectable odor was noted at all exposure levels (2 to 6 ppm). No eye irritation was noted at all concentrations exposed. The odour threshold is given as 6.667 mg/m3 and the irritating concentration as 10.00 mg/m3.
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