Registration Dossier
Registration Dossier
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EC number: 269-123-7 | CAS number: 68187-76-8
Endpoint summary
Administrative data
Description of key information
IC50, 48h (Algae) = 46 mg/l (growth rate, active ingredient)
EC50, 48h (Daphnia Magna) = 4.3 mg/l
EC50, 96h (fish) = 5.4 mg/l
EL50, repro, Dapnia, 21d > 10 mg/l (test item)
NOELR (FELS, lenght) ca 1 mg/l (test item), 0.62 mg/l (active ingredient, 62 -64% wt)
Additional information
The substance has reliable tests for all the trophic levels for the acute and long term exposures.
Effetcs are observed for all the tests. While in the acute tests Daphnia and Fish present comparable results, in the long term tests, Fish demonstrated as the most sensitive species and the relevant effect oberved has been a reduction in the lenght of the juvenile fish that sets the NOELR ca. 1 mg/l (test item), i.e. 0.62 mg/l (active ingredient, 62 -64% wt).
Based on the chemical nature of the substance, no specific analytical technique is available, but the non-selective TOC analysis was performed for the determination of the test concentrations. Moreover, the dissolution of the substance in the different tests (normal shaking vs WAF technique) had a small impact in the final solubilisation of the substance, expecially when compared short to long term toxicity studies.
Moreover, based on the fish sensitivity to the test item, the demonstration of equilibrium attained of the WAF solutions and verification of their stability during the long term toxicity daphnia was not considered necessary to be repeated, and the results were reported as loading rates. Finally, Daphnia did not show any effects up to the highest tested loading rates.
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