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EC number: 200-712-3 | CAS number: 69-72-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In a 72-h acute toxicity test, cultures of Scenedesmus subspicatus were exposed to salicylic acid at different concentration (no more data).
The study follows the OECD guideline 201 "Alga, growth inhibition test".
The 72-h EC50 based on cell density was > 100 mg/L.
The percentage of growth inhibition was not mentionned.
No abnormalities were mentionned.
Therefore, in the test conditions, salicylic acid is not hazardous to algae according to Directive 67/548/EEC criteria.
Key value for chemical safety assessment
Additional information
Five toxicity studies on algae are available for salicylic acid. None of them has been performed with pH adjustment therefore it is not possible to discriminate between acidic pH effect and salicylic acid toxic effect. Some tests were carried out in the same conditions but with sodium salicylate, which does not lower the pH as salicylic acid (Wang & Lay, 1989). These demonstrated no effect at the same tested concentrations, highlightening that mainly low pH could be responsible for the observed growth inhibition. The data of Henschel et al. (1997) has been nevertheless selected as key study since conducted in accordance with the OECD guideline 201. The EC50 value being above 100 mg/L, this study has been considered as still reliable for the assessment of the hazardous profile of the substance, even if the toxic effect may have been overestimated.
Conclusion:
72h EC50 > 100 mg/L.
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