Registration Dossier
Registration Dossier
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EC number: 202-588-6 | CAS number: 97-52-9
Endpoint summary
Administrative data
Description of key information
2-Methoxy-4-nitroaniline was tested after dermal and oral treatment of rats.
After dermal treatment no adverse effects were observed at a dose of 2000 mg/kg bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 1 260 mg/kg bw
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- discriminating dose
- Value:
- 2 000 mg/kg bw
Additional information
The oral LD 50 was determined separately for male and female animals. Female animals proved more sensitive and showed a LD50 of 1260 mg/kg bw while for male animals the LD 50 was 2000 mg/kg bw.
Dermal treatment of rats caused no adverse effects at a dose of 2000 mg/kg bw.
Toxicity after inhalation was not tested.
Justification for classification or non-classification
Classified R22, harmful if swallowed, according to the oral LD50 in female rats
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