Registration Dossier
Registration Dossier
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EC number: 209-691-5 | CAS number: 590-86-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Based on mean measured concentrations, the LC50 (96 h) for fish (Pimephales promelas) is 3.25 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 3.25 mg/L
Additional information
Isovaleraldehyde was tested on fathead minnows (Pimephales promelas) in a 96-h flow-through acute study. No specific guideline was reported, but documentation is sufficient to assign validity and good reliability. The test design is similar to OECD 203. Five test concentration and 1 control were set up. One test chamber with 20 fish was used per test concentrations. The test concentrations were analytically verified by GLC every day in each test chamber (recovery: 106.7±4.9%).
Concentrations were as follows:
nominal: 0 (control), 2.80, 4.32, 6.63, 10.2, and 15.7 mg/L
measured (corrected average): <0.61, 2.07, 2.66, 4.13, 6.65, and 10.7 mg/L
Mortalities and signs of abnormal behaviour were observed in the all concentrations. All fish died in the two highest concentrations. Based on mean measured concentrations, the 96-h LC50 was 3.25 mg/L.
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