Registration Dossier
Registration Dossier
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EC number: 269-103-8 | CAS number: 68187-51-9 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77496.
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Bayer - short report
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 978
- Report date:
- 1978
Materials and methods
- Principles of method if other than guideline:
- application: oral
animals: male rats, 180-240 g, Wistar
application medium: water dose: 10 g/kg
observation time: 14 days
calculation LD50: probit analysis - GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Zinc ferrite brown spinel
- EC Number:
- 269-103-8
- EC Name:
- Zinc ferrite brown spinel
- Cas Number:
- 68187-51-9
- Molecular formula:
- ZnFe2O4
- IUPAC Name:
- Zinc ferrite brown spinel
- Test material form:
- solid: particulate/powder
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- water
- Doses:
- 10000 mg/kg
- No. of animals per sex per dose:
- 10
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 10 000 mg/kg bw
- Clinical signs:
- other:
Applicant's summary and conclusion
- Executive summary:
Single oral application of 10000 mg/kg bw AC 5070 in male rats. During post-obserservation
time of 14 days none of the animals died.
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