Registration Dossier
Registration Dossier
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EC number: 216-904-5 | CAS number: 1694-31-1
Carcinogenicity
Administrative data
- Endpoint:
- carcinogenicity
- Remarks:
- other: no data
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 1694-31-1
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:- Commercial
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- FDA Cancer Female Mouse: Multicase model AF4.
- GLP compliance:
- no
Test material
- Reference substance name:
- 3,3-dimethylbutyryl chloride
- EC Number:
- 216-904-5
- EC Name:
- 3,3-dimethylbutyryl chloride
- Cas Number:
- 1694-31-1
- Molecular formula:
- C8H14O3
- IUPAC Name:
- 3,3-dimethylbutyryl chloride
- Test material form:
- liquid
- Details on test material:
- - Name of test material : tert-butyl 3-oxobutanoate- Molecular formula : C8H14O3- Molecular weight : 158.196 g/mol- Smiles notation : O(C(C)(C)C)C(CC(C)=O)=O- InChl : 1S/C8H14O3/c1-6(9)5-7(10)11-8(2,3)4/h5H2,1-4H3- Substance type : Organic- Physical state : Liquid
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- female
Administration / exposure
- Route of administration:
- other: no data
- Type of inhalation exposure (if applicable):
- not specified
- Vehicle:
- not specified
Results and discussion
Effect levels
- Based on:
- test mat.
- Sex:
- female
- Basis for effect level:
- other: Non carcinogenic
- Remarks on result:
- other: Effect type: carcinogenicity (migrated information)
Applicant's summary and conclusion
- Conclusions:
- The substance is non carcinogenic in female mice.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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