Registration Dossier
Registration Dossier
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EC number: 617-268-5 | CAS number: 81919-14-4
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Description of key information
Source: ACRAF Investigator's brochure Title "0.5% Benzadac Lysine eye drops (Bendalina)"
Toxicity to reproduction: other studies
Additional information
Reproductive toxicology studies, performed by oral route administration of benzadac lysine, showed that doses up to 50 mg/kg in mice, 200 mg in rats, 30 mg in rabbits did not influence the fertility and general reproductive performance, as well as the postnatal development, nor they caused embryotoxic of teratogenic effects. The findings at higher doses were mainly related to maternal toxicity.
Justification for classification or non-classification
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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