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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
toxicity to terrestrial arthropods: short-term
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1999
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study according EU/OECD guideline

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2002

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
ISO 11267 (Inhibition of Reproduction of Collembola by Soil Pollutants)
GLP compliance:
yes (incl. QA statement)
Application method:
soil

Test material

Constituent 1
Chemical structure
Reference substance name:
4-chloro-N-cyclopentylbenzylamine
EC Number:
266-097-9
EC Name:
4-chloro-N-cyclopentylbenzylamine
Cas Number:
66063-15-8
Molecular formula:
C12H16ClN
IUPAC Name:
N-[(4-chlorophenyl)methyl]cyclopentanamine

Sampling and analysis

Analytical monitoring:
no

Test substrate

Vehicle:
yes

Test organisms

Test organisms (species):
Folsomia sp.
Animal group:
Collembola (soil-dwelling springtail)

Study design

Study type:
laboratory study
Limit test:
no
Total exposure duration:
28 d

Results and discussion

Effect concentrationsopen allclose all
Duration:
28 d
Dose descriptor:
LC50
Effect conc.:
672.3 mg/kg soil dw
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Fisher exact test, a = 0.05
Duration:
28 d
Dose descriptor:
LC50
Effect conc.:
511.3 mg/kg soil dw
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
reproduction
Remarks on result:
other: Dunnett test, a = 0.05, one sided smaller
Duration:
28 d
Dose descriptor:
LOEC
Effect conc.:
1 000 mg/kg soil dw
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Fisher exact test, a = 0.05
Duration:
28 d
Dose descriptor:
LOEC
Effect conc.:
500 mg/kg soil dw
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
reproduction
Remarks on result:
other: Dunnett test, a = 0.05, one sided smaller
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
500 mg/kg soil dw
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Fisher exact test, a = 0.05
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
250 mg/kg soil dw
Nominal / measured:
meas. (initial)
Conc. based on:
test mat.
Basis for effect:
reproduction
Remarks on result:
other: Dunnett test, a = 0.05, one sided smaller

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
NOEC (mortality and reproduction): 250 mg/kg artificial soil dry weight soil.