Registration Dossier
Registration Dossier
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EC number: 607-821-9 | CAS number: 25858-24-6
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- no data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Insufficient documentation for an assessment of reliability.
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 988
- Report date:
- 1988
Materials and methods
- Principles of method if other than guideline:
- No data
- GLP compliance:
- not specified
- Test type:
- other: No data
Test material
- Reference substance name:
- (+-)-TRANS-3-METHYL-1-[(4-METHYLPHENYL)SULFONYL]-4-PHENYLPIPERIDINE-4-CARBONITRILE
- Cas Number:
- 25858-24-6
- Molecular formula:
- C20H22N2O2S
- IUPAC Name:
- (+-)-TRANS-3-METHYL-1-[(4-METHYLPHENYL)SULFONYL]-4-PHENYLPIPERIDINE-4-CARBONITRILE
- Details on test material:
- No data
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No data
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Details on oral exposure:
- No data
- Doses:
- 640 mg/kg bw
No other concentrations mentioned - No. of animals per sex per dose:
- No data
- Control animals:
- not specified
- Details on study design:
- No data
- Statistics:
- No data
Results and discussion
- Preliminary study:
- No data
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- > 640 mg/kg bw
- Mortality:
- No data
- Clinical signs:
- other: No changes in behaviour and no toxic effects.
- Gross pathology:
- No data
- Other findings:
- No data
Any other information on results incl. tables
Not applicable
Applicant's summary and conclusion
- Conclusions:
- The oral LD50-value of T000268 is > 640 mg/kg bw.
- Executive summary:
Not applicable
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