Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
density
Remarks:
density
Type of information:
experimental study
Adequacy of study:
other information
Study period:
29 June 2009 - 22 September 2009
Reliability:
1 (reliable without restriction)

Data source

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
other: ECHA Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7a: Endpoint Specific Guidance, May 2008
GLP compliance:
not specified
Type of method:
other: Gas pycnometer

Test material

Constituent 1
Chemical structure
Reference substance name:
(2E)-2-cyano-N-(2,4-dichloro-5-methoxyphenyl)-3-({4-methoxy-3-[3-(4-methylpiperazin-1-yl)propoxy]phenyl}amino)prop-2-enamide; propan-2-ol
EC Number:
700-456-7
Cas Number:
1333490-26-8
Molecular formula:
C26H31Cl2N5O4 · 1/2(C3H8O1)
IUPAC Name:
(2E)-2-cyano-N-(2,4-dichloro-5-methoxyphenyl)-3-({4-methoxy-3-[3-(4-methylpiperazin-1-yl)propoxy]phenyl}amino)prop-2-enamide; propan-2-ol
Details on test material:
Molecular weight: 548.47
Batch: 09-002
Purity: >92% (Contains 6.5% isopropanol as a hemi-solvate
Appearance: Yellowish solid

Results and discussion

Density
Type:
density
Density:
ca. 1.324 g/cm³
Temp.:
22.8 °C

Applicant's summary and conclusion