Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 213-600-4 | CAS number: 993-00-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No data are available for chloro(methyl)silane. A 48-hour EC50 of 124 mg/L has however been determined for the effects of a read-across substance, Trimethylsilanol (CAS 1066-40-6), on mobility of Daphnia magna. A NOEC of <60 mg/L has been determined in the same test. A 48-hour EC50 value of >117 mg/L and NOEC of ≥117mg/L have been determined for the effects of a second read-across substance, dimethylsilanediol, 1066-42-8, on mobility of D. magna. The results of the test with trimethylsilanol (CAS 1066-40-6) have been selected as the key results because they are definitive values.
Key value for chemical safety assessment
Additional information
No test data for short-term toxicity to aquatic invertebrates are available for Chloro(methyl)silane. However reliable data for short-term toxicity to invertebrates are available for the related substances Dimethylsilanediol, 1066-42-8, and Trimethylsilanol, 1066-40-6. The hydrolysis half-life of Chloro(methyl)silane indicates that, under conditions relevant to the short-term invertebrate test, hydrolysis to Dimethylsilanol and hydrogen chloride will occur. The properties of hydrogen chloride are well characterised and are discussed in the CSR. Its effects on aquatic organisms are limited to those that result from changes to pH in unbuffered media. Read-across from trimethylsilanol and dimethylsilanediol to dimethylsilanol is appropriate because all are small molecule alkylsilanols containing Me-Si and HO-Si groups; their properties are expected to be similar.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
