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Diss Factsheets
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EC number: 200-087-7 | CAS number: 51-28-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The majority of data have been obtained from secondary source (EPA databank).
For 2,4 -dinitrophenol data for fresh and marine ecosystems are available for all three trophic levels (alga, crustacean and fish). Furthermore data on microorganisms and other aquatic organisms are also available.
On the base on ecotoxicity data, 2,4 -dinitrophenol is very toxic to aquatic for algae and crustaceans, but especially for fish.
In fact, the most conservative LC50 and NOEC for freshwaterfish are 390 µg/L and 208 µg/L, respectively. The most conservative data on algae and crustaceans are in any case low, on the range of 1 -5 mg/L.
The same toxicity can be observed for marine water, with an LC50 fish of 1500 µg/L , a NOEC fish of 940 µg/L and a range of toxicity for algae and crustaceans of 5- 20 mg/L.
2,4-dinitrophenol is very toxic also for biodegrader microrganisms. In an aerobic biodegradation and in a biodegradation under methanogenic conditions with anaerobic digester sludge studies the toxic level of c.a 10 -20 mg/L of 2,4-dinitrophenol was defined, and a detailed study on sludge activity has setted a NOEC (no inhibitory effect) at 4 ppm of 2,4-dinitrophenol.
2,4- dinitrophenol can be harmful for other aquatic organisms as data on Aedes aegypti Yellow Fever Mosquito Chironomids as Tanytarsus dissimilis Midge show (LC50 5-10 mg/L and LC50 of 48.1 mg/L, respectively). This latter organism, in its first larval stage, lives also in sediment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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