Registration Dossier
Registration Dossier
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EC number: 247-477-3 | CAS number: 26140-60-3
Repeated dose toxicity: inhalation
Administrative data
- Endpoint:
- short-term repeated dose toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only abstract available, journal is in Russian.
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicity of p-terphenyl
- Author:
- Khromenko ZF
- Year:
- 1 972
- Bibliographic source:
- USSR. Nauch. Tr., Irkutsk. Med. Inst. No. 115
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- p-terphenyl
- EC Number:
- 202-205-2
- EC Name:
- p-terphenyl
- Cas Number:
- 92-94-4
- Molecular formula:
- C18H14
- IUPAC Name:
- 1,1':4',1''-terphenyl
- Details on test material:
- The study was done on one of the isomers (p-terphenyl) which is only present in the registration substance in minor concentrations.
Constituent 1
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Details on inhalation exposure:
- Concentrations:
- 3 mg/m3
- 35 mg/m3 - Analytical verification of doses or concentrations:
- not specified
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
- Conclusions:
- After chronic exposure to 35 mg/m3 air, functional and morphological changes in the organs were observed. At a concentration of 3 mg/m3 this was not the case. The approximated maximum permissible concentration in air of working areas is therefor recommended to be 5 mg/m3.
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