Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Not skin irritant

Not eye irritant

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

For skin irritation test the skin was tested intact and scarified in one flank of six rabbits and the other side of the body was used as control. Erythema was not assessed due to discolouration of the skin while edema was assessed only at 24 and 72h. For classification purporse the worst value between 24 and 72h was set for the time point 48h. Under the experimental conditions the substance did not show any skin irritation proeprites.

Moreover a study carried out on a similar substance, whose molecular structure is similar to the one of the Target Substance, shows the tested substance is not skin irritant.

Considering the results of the test conducted on the substance in itself and on the similar substance and the results of the eye irritation test conducted, no skin irritation potential is expected.

For the eye irritation test, one eye was instilled while the other was used as control. Conjuncitva, iris and cornea were assessed at 24, 48 and 72h withotìut showing any eye irritative properties.

Justification for classification or non-classification

The substance is not eye or skin irritant and is not classified under Regulation 1272/2008.