Registration Dossier
Registration Dossier
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EC number: 600-593-1 | CAS number: 104632-26-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 986
- Report date:
- 1986
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Akute Toxizitätsprüfung nach peroraler ~pplikation an Chbb:THOM-Ratten
Versuch Nr. 25/86
und der dazugehörige Bericht vom 28.07. 1986
wurden entsprechend § 58.35 Absatz b der Good Laboratory Practi ce Regu-
1ations der Food and Drug Administration, U.S.A. bzw. dem Abschnitt 11
2.2.(e) der OECD-Grundsätze der Guten Labor Praxis (GLP) von der Qualitätssicherungseinheit
inspiziert und überprüft. - GLP compliance:
- yes
- Test type:
- acute toxic class method
Test material
- Reference substance name:
- 104632-25-9
- Cas Number:
- 104632-25-9
- IUPAC Name:
- 104632-25-9
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: Chbb: THOM
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: drinking water
- Vehicle:
- water
- Doses:
- 100,200,400,560,800 mg/kg
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- >= 809.4 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Conclusions:
- Bei Dosierungen von 200 bis 800 Mg/kg (Tierhaltung In Drahtkaefigen) und einer Beobachtungszeit von 14 Tagen wurden
folgende LD 50 - Werte ermittelt :
24 Stunden Beobachtungszeit : m > 800 mg/kg - f 851,6 mg/kg - m + f 957,4 mg/kg
7 und 14 Tage Beobachtungszeit : m > 800 mg/kg - f 548,0 mg/kg - m + f 809,4 mg/kg
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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