Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 27 September 2022 - 24 November 2022
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 022
- Report date:
- 2022
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 496: In vitro Macromolecular Test Method for Identifying Chemicals Inducing Serious Eye Damage and Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- D‐Glucopyranose, oligomeric, C10‐16‐alkyl glycosides, 3‐(3,4‐dicarboxy‐3‐hydroxy‐1‐oxobutoxy)‐2‐hydroxypropyl ethers, sodium salts
- Cas Number:
- 2481100-10-9
- Molecular formula:
- not applicable (UVCB substance)
- IUPAC Name:
- D‐Glucopyranose, oligomeric, C10‐16‐alkyl glycosides, 3‐(3,4‐dicarboxy‐3‐hydroxy‐1‐oxobutoxy)‐2‐hydroxypropyl ethers, sodium salts
- Details on test material:
- - Name of test material (as cited in study report): Suga®Citrate L1C
- Physical state: clear viscous liquid
- Purity: ca. 40% AS
Constituent 1
Test animals / tissue source
- Species:
- human
Test system
- Vehicle:
- unchanged (no vehicle)
- Controls:
- other:
Results and discussion
In vitro
Results
- Irritation parameter:
- other: MQS Score
- Value:
- 47.4
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (irreversible effects on the eye) based on GHS criteria
- Conclusions:
- The test item had an MQS score of 47.4 and according to OECD TG 496 is predicted to be classified as UN GHS Category 1.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
