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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Water solubility:
> 100 g/L
Conc. based on:
test mat.
Loading of aqueous phase:
100 g/L
Incubation duration:
24 h
Temp.:
20 °C
pH:
7
Remarks on result:
other: The pH value is assumed and was not determined.
Details on results:
Flask A: A clear solution was obtained after 1 minute of stirring. No phase separations or sedimentations were observed over a time period of 24 hours.
Flask B: A slightly turbid mixture was obtained after 5 minutes of stirring. This mixture was stable without any visible changes over a time period of 24 hours.
Flask C: A highly turbid mixture was obtained after 30 minutes of stirring. This mixture was further instable over a time period of 24 hours. Sedimentations were observed and the mixture became highly viscous and stayed very turbid.

Due to the clear solution in flask A it is justifiable to state that the water solubility of the test item RFR 6634 is > 100 g/L.

Conclusions:
The water solubility of RFR 6634 was determined to be > 100 g/L.
Executive summary:

Solubility tests of the test item in demineralized water were prepared in the following ratios: 1:10, 1:1 and 10:1. A ratio of 1:10 (test item/water) resulted in a clear liquid. Accordingly, the water solubility of RFR 6634 was determined to be > 100 g/L.

Description of key information

Solubility tests of the test item in demineralized water were prepared in the following ratios: 1:10, 1:1 and 10:1. A ratio of 1:10 (test item/water) resulted in a clear liquid. Accordingly, the water solubility of RFR 6634 was determined to be > 100 g/L.

Key value for chemical safety assessment

Water solubility:
100 g/L
at the temperature of:
20 °C

Additional information

100 g/L should read: > 100 g/L