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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
basic toxicokinetics, other
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence

Data source

Materials and methods

Objective of study:
absorption

Test material

Constituent 1
Reference substance name:
Glycerides, C10-20 and C10-20-unsatd., oxidized
EC Number:
295-734-3
EC Name:
Glycerides, C10-20 and C10-20-unsatd., oxidized
Cas Number:
92128-40-0
Molecular formula:
Not available
IUPAC Name:
Glycerides, C10-20 and C10-20-unsatd., oxidized
Constituent 2
Chemical structure
Reference substance name:
Docosanoic acid
EC Number:
204-010-8
EC Name:
Docosanoic acid
Cas Number:
112-85-6
Molecular formula:
C22H44O2
IUPAC Name:
docosanoic acid
Test material form:
liquid

Results and discussion

Preliminary studies:
Molecular weight above 500 and Log P > 4 of the substance suggests a weak dermal absorption, 10 % in a worse case and none in better case (EC, 2004; TGD, 2003).
Main ADME results
Type:
absorption
Results:
In conclusion, based on the available information, the physicochemical properties and molecular weight of oxidised corn oil suggest low oral and dermal absorption.

Applicant's summary and conclusion

Conclusions:
Based on the available information, the physicochemical properties and molecular weight of oxidised corn oil suggest low oral and dermal absorption.